ANGUISH
NOUNS
► AMARITUDE anguish; distress; the quality of being bitter to the mind or feelings → 1490 chiefly poetic usage
► HEART-RENDING mental anguish; terrible distress;; torment → 1854
► SYTE anguish, grief; suffering; a feeling of anguish or grief→ 1175 obs.
Lexicophilia 