Reverse Dictionary: IRRITATE

ADJECTIVES
► ACRID of irritating and bitter temper or manner → 1681
► AG angry, annoyed, irritated, aggravated → 1997 US students’ sl.
► AGGRAVATED irritated, provoked → 1611
► AGGRAVATING irritating, annoying → 1685 colloq.
► AGGRO aggravated, irritated, annoyed → 2000 Amer. sl. (Bk.)
► ALL MUGGLED UP confused and irritated → 1984 Amer. dial.
► ANGERSOME vexatious, annoying, irritating, troublesome → 1650 obs. exc. Sc.
► ANNOYOUS irritating, annoying → 1400 arch.
► ANTAGONIZING irritating, annoying → 1896
► ARSEHOLE irritating, contemptible, despicable → 1956
► ASS-GRABBING annoying, vexatious, irritating → 1965 Amer. sl.
► ASSHOLE stupid, irritating, contemptible, despicable → 1888 US sl.
► BALL-BREAKING troublesome, difficult, very irritating, physically demanding, exhausting → 1959 US sl.
► BALL-BUSTING troublesome, difficult; irritating; physically demanding, exhausting  → 1944 US sl.
► BALLS-ACHING irritating, annoying → 1912 UK sl.
► BASK irritating or bitter to the senses → 1175 obs. exc. Eng. dial.
► BOTHERSOME irritating, annoying, troublesome → 1817
► BRASSED OFF irritated, fed up, annoyed → 1940 sl.
► BRIDLING showing irritation or anger → 1673
► BRINGLY irritated, angry → 1983 UK sl.
► BROIGUS irritated; angry → 1937 especially Jewish usage
► BROWNED OFF irritated, annoyed → 1916 sl., orig. military usage
► BROWNED UP irritated, annoyed → 1937 UK sl.
► BUGGED angry, irritated, annoyed → 1947
► BUGGIN’ irritated; perturbed → 20C teen & high school sl.
► BULL-GOADED extremely irritated → 1964 Amer. dial.
► BUMKICKED irritated, depressed → 1967 US sl.
► BUNCHED UP irritated, tetchy → 2004 US sl.
► BURNED OUT irritated, annoyed → 1992 Ireland
► CAGGED ► KEGGED irritated, angry, annoyed, vexed, offended; grieved → 1811 Sc. & Eng. dial. (Bk.)
► CHAFED angered, irritated, vexed → 1330
► CHIPPY angry, irritated → 1894 UK sl.
► CRABBED irritated, irate, vexed; out of humour → 1480
► CROSS AS TWO STICKS very irritated, angry, or annoyed → 1763
► DAMFOOL ► DAMN-FOOL  damnably foolish; silly; stupid and irritating → c1895 colloq.
► DANDERY irritated; angry; alarmed → 1838 US sl.
► DANGFOOL stupid and irritating → L19 sl.
► DARNFOOL wretched, nasty; silly; stupid and irritating → 1780s
► DEMENTED extremely irritated, annoyed, wowrried → 1632
► DIDDLEY-DAMN ► DIDDLY-DAMN irritating, insignificant → 1966 Amer. dial.
► DISEASING irritating, annoying, troublesome → 1425 obs.
► DRAG-ASS irritating, annoying → 1930 US sl.
► DRATTED ► DROTTED irritating, infuriating → 1834 sl.
► DRUGGED irritated, annoyed → 1960 US sl.
► EGGY angry, irritated, annoyed → 1935 colloq.
► ENCHAFED irritated, furious, excited → 1616
► ERKIN’ irritating, annoying → 2000 African-American sl.
► EXASPERATIVE irritating, exasperating → 1837
► EXULCERATED irritated, embittered, exasperated → 1640
► FED UP irritated, annoyed, bored → 1895 sl.
► FED UP TO THE BACK TEETH irritated, annoyed, bored → 1919  sl.
► FUCKED-OFF angry; annoyed, irritated → 1923 sl., chiefly UK
► FULL UP TO THE BACK TEETH irritated, annoyed, bored → 1921 Aust. sl.
► GALLED irritated, vexed → 1601
► GALLING irritating, offensive to the mind or spirit → 1583
► GOAT-GETTING irritating, annoying → 1908 colloq.
► GRATING irritating, fretting, wearing → 1563
► GRIEVED irritated, incensed, made angry → 1400 obs.
► HACKED ► HACKED OFF angry, irritated; annoyed and disappointed → 1892 sl., orig. US
► HACKED UP angry, annoyed; irritated; confused; tired→ 1984 Amer. sl.
► HIPPED irritated, angry → 1864 UK sl. (Bk.)
► HOHA irritated, tetchy, fed up → 1972 NZ Maori
► HONKED OFF irritated, annoyed, angry → 1962 colloq.
► HUMPTY irritated, tetchy → 1970 sl.
► IMPORTUNABLE irritating, annoying → 1566 obs.
► IMPORTUNATE irritating, annoying, irksome → 1500
► IRKING irritating, troublesome → 1898 Sc.
► IRRITANT causing irritation; irritating → 1828
► IRRITATIVE tending to irritate, irritating, annoying → 1878
► IRRITATORY causing irritation; irritating → a1656 
► JACKED ► JACKED OUT annoyed, irritated, angry → 1980 US students’ sl.
► JAGGED irritating; depressed → 1988 NZ sl.
► JERK deliberately irritating or obnoxious → 1947
► JERKISH deliberately irritating or obnoxious → 1948 colloq.
► LEMONY 1. irritating, frustrating → 1926 Aust. sl.
2. irritated, angry → 1935 Aust. & NZ sl.
► MADDENED irritated, annoyed → 1735
► MADDENING irritating, vexing → 1743
► MAGGED irritable, irritated → L19 colloq.
► MESSY fidgeting, irritating, finicking → 1905 Eng. dial. (Bk.)
► MIFFISH easily offended or irritated → 1790
► MIFFY easily irritated or offended → 1810 colloq.
► MONSTER irritating, annoying → 1953 African-American sl.
► MOTHERING contemptible or irritating → 2004 African-American sl., potentially offensive
► MUGGLED UP confused and irritated → 1984 Amer. dial.
► NAGGING irritating → 1807
► NAPPY disgusting, irritating,  unpleasant, worthless → 1977 US teen sl., derogatory
► NARKED peeved, irritated, annoyed → 1888 sl.
► NEEDLED irritated, peevish, angry → 1879 sl.
► NEEDLING irritating, annoying → 1839
► NETTLED irritated, vexed, provoked, annoyed, angry → 1576
► NETTLESOME irritating, irksome, vexatious → 1845 chiefly US
► NETTLING irritating, annoying, provoking → 1607
► NIFFED irritated; put out → 1880 chiefly colloq. & Eng. dial.
► NIGGLED annoyed, irritated, esp. when made so by disappointed or the pettiness of others → 1878 UK sl.
► NIGGLING irritating or troublesome in a petty way → 1854
► NOXIOUS irritating, tiresome → 1847
► NUISANCY irritating, annoying; causing a nuisance → 1906 colloq.
► ON SOMEONE’S BACK being irritating, causing problems for someone → 1832 sl.
► ON THE FRET irritated, agitated → 1688
► ON THE GEE irritated, annoyed → 1923 sl.
► ON THE RAG irritated, irritable, testy, bad-tempered → 1960s sl.
► PEED OFF irritated, angry → 1948 US sl.
► PEEVED irritated, annoyed → 1908
► PESTIFEROUS irritating, annoying → 1600 colloq.
► PESTILENTIAL irritating, annoying → 1833 colloq.
► PIN-PRICK causing a minor irritation or petty annoyance → 1898
► PINPRICKING irritating, causing petty annoyance → 1881
► PIPPED ► PIPPED OFF irritated, annoyed → 1914 colloq.
► PIPPISH irritated, out of sorts → 1914 UK sl.
► PIPPY irritated, out of sorts → 1886 Aust. sl.
► PIQUING irritating, provoking → 1794
► PISSED ► PISSED OFF angry, irritated; fed up, depressed → 1943 sl., orig. US
► PISS-OFF irritating, annoying → 2000 UK sl.
► PISSY irritated, angry → 1962 sl.
► POOPY unpleasant, irritating, disagreeable → 2009 Amer. sl., euphemism for ‘shitty’ (Bk.)
► PROVOCATIVE irritating, challenging, stimulating → 1600
► PROVOKED irritated, annoyed, angry → 1538
► PROVOKING irritating, annoying, exasperating → 1643
► RAGGY annoyed, irritated → 1900
► RASPISH irritating, irritable → 1854
► RATTY irritated, annoyed, obstreperous → 1897 colloq.
► RILED irritated, annoyed, vexed → 1825
► RILEY angry, irritated → a1824 Amer. dial.
► RILING irritating, annoying → 1860
► RIPE irritated, angry → 1966 UK sl.
► RUBBED irritated, annoyed → 1927
► RUFFLED discomposed, irritated, stirred up → 1659
► RUFFLING causing irritation or annoyance → 1680
► SALTY ill-tempered, angry, irritated, resentful, annoyed → 1925 Amer. dial.
► SALTY AS LOT’S WIFE aggressive, angry, irritated → 1945 US Western usage (Bk.)
► SCOTTY irritated, annoyed → 1867
► SMARTFUL stinging, irritating → 1839
► SNAKE-HEADED irritated, testy, angry → 1900 Aust. sl.
► SNARKED OFF irritated, upset → 2003 NZ sl.
► SNORTY irritated, peevish → 1893 colloq.
► SNOTTY irritated, angry → 1812 sl.
► SODDISH irritating, annoying → 1922 UK sl.
► SORE ► SORE ABOUT inclined to be irritated or grieved → 1694 colloq.
► STANK contemptible, irritating → 2010 African-American sl.
► STINGING causing sharp mental pain or irritation → a1225
► STREAKY irritated, ill-tempered → 1848 US sl.
► T’D ► TEED ► TEED OFF irritated; annoyed → 1941
► TEASED irritated or annoyed in a petty way → 1627
► TEASING pettily irritating, annoying, or vexatious → 1694
► TEASY teasing, irritating → 1901
► TECHY ► TETCHIE ► TETCHY ► TITCHIE ► TITCHY easily irritated or made angry; short-tempered → 1592
► TEMPERED angry, irritated, annoyed, upset → 1942 Amer. dial.
► TEPTIOUS snappish, captious; irritating; treacherous, changeable, not to be depended upon → 1876 Eng. dial.
► THORNY harassing, vexatious, irritating → 1340
► TICKED ► TICKED OFF irritated, annoyed → 1928 sl., orig. US
► TITILLATING tickling or irritating → 1684 obs.
► TITILLATORY tickling or irritating → 1862 obs.
► TWEAGUEY irritated, angry → 1785 sl. (Bk.)
► UP IN FEATHERS annoyed, irritated → 1969 Amer. dial.
► UP IN ONE’S HAIR irritating, pestering → 2003 UK sl.
► UP IN THE AIR annoyed, irritated; anxious, upset → 1901 Amer. dial.
► UP IN THE BOUGHS angry, irritated → 1698 sl.
► UP IN THE SKY annoyed, irritated → 1965 US sl.
► UP ONE’S ASS immediately behind, hence irritating, bothering → 1970 sl.
► UP ONE’S BUTT immediately behind, hence irritating, bothering → 1970s sl.
► UP ONE’S HOLE immediately behind, hence irritating, bothering → 1970s sl.
► UPON THE FRET irritated, agitated → 1679
► UP THE POLE annoyed, irritated → L19 nautical sl.
► URGING of words: taunting, irritating → 1655 Eng. dial.
► VELLICATIVE causing irritation or twitching → 1822
► WAMBLE-CROPPED ► WOMBLE-CROPPED unhappy, discomfited, irritated; dissatisfied; offended → 1798 Amer. dial.
► WILD extremely irritated or vexed; angry → 1653
► WIRED ► WIRED UP irritated, provoked → 1890 sl. (Bk.)
► WOOD violently angry or irritated, enraged → 1205 obs.
► WOUND-UP annoyed, tense and irritated → 1919 sl.
► WOUND UP LIKE AN EIGHT-DAY CLOCK annoyed, tense and irritated → 1957 sl.
► WOUNDY annoyed, tense and irritated → 1910s sl.
► WRONG irritating, contrary → 1967 African-American & students’ sl.
► WROTH of animals; irritated, enraged; of a violent or fierce nature → a900 obs.
► X annoyed, irritated, angry, cross → 1962 UK sl.

INTERJECTIONS & PHRASES
► AG! an exclamation of pleasure, irritation, or exasperation → 1936 S. Afr.
► AM I BURNED UP! am I angry! am I irritated! → 1920s
► AM I IRRIGATED! am I irritated → 1930s
► BLAST MY EYES! ► BLAST YOUR EYES! an exclamation of irritation, impatience, annoyance, etc. → 1756 sl.
► BLAST THEIR HIDE! an exclamation of irritation, impatience, etc .→ 1948 sl.
► BLAST YOUR EYES AND LIMBS! an exclamation of irritation, impatience, etc. → 1756 sl.
► BLOUSENART! an exclamation of irritation → 2014 W. Indies
► BUZZKILL! ► BUZZSTOMP! an exclamation of disappointment and irritation; too bad! that’s awful! → 1989 US students’ sl.
► BY THE FERRUPS expresses irritation, impatience, astonishment, etc. → 1860 Eng. dial., obs.
► BY THE TOMBS! an exclamation of irritation → 1899 US sl.
► CASE OF THE REDS a state of irritation at the world → 1990 US teen sl.
► CHINGAO! an exclamation of irritation; what the fuck! → 1993 US sl.
► CHINGOW! an exclamation of irritation; what the fuck! → 1997 US sl.
► COBBLERS! an exclamation of irritation; balls! → 1979 sl.
► COME ON! an exclamation of irritation, disbelief, disapproval → 1901 sl.
► CROP ME! an exclamation of irritation or annoyance → 1760 UK sl.
► CURSES! used to express irritation or frustration → 1801
► DAD BURN! ► DAG BURN! blast it! an exclamation of surprise, irritation or frustration → 1829 Amer. sl.
► DAMN! ► DAMN IT!  an exclamation of disappointment, irritation, annoyance, frustration, etc. → 1589
► DAMNATION SEIZE THE DICE! an exclamation of irritation or impatience → 1877
► DAMNATION SEIZE THEE! an exclamation of irritation or impatience → 1759
► DAMNATION TAKE HIM! an exclamation of irritation or impatience → 1613
► DAMN MY EYES! ► DAMN YOUR EYES! an exclamation of irritation, impatience, annoyance, etc. → 1732 UK sl.
► DANG! an exclamation of disappointment, irritation, frustration, etc. → 1821
► DANG IT! damn! an exclamation of disappointment, irritation, frustration, etc. → L18 euphemism
► DARN! damn!; an exclamation of disappointment, annoyance, irritation, frustration, etc. → 1781
► DEAR! ► DEAR OH DEAR! a mild register of anxiety, irritation, regret, etc. → 1694
► DERN! ► DERN IT! ► DURN! ► DURN IT! an exclamation of disappointment, irritation, frustration, etc. → 1780s euphemism
► DICKENS!, THE expresses irritation, exasperation, etc. → 1697 arch.
► FFS! an exclamation of irritation or disbelief (For Fuck’s Sake) → 2014 US sl.
► FML an exclamation of irritation or frustration (Fuck My Life) → 2014 US sl.
► FOR CRYING OUT LOUD! for Christ’s sake! used to express anger, irritation, surprise, astonishment, etc. → 1924 euphemism
► FOR THE LOVE OF HEAVEN! an exclamation of irritation → 1687 sl.
► FUCKSTICKS! an exclamation of irritation → 2018 sl.
► GOD ROT THEM! expresses irritation or impatience → 1980
► GREAT PIP! an exclamation of surprise or irritation → 1901 UK sl.
► GREAT SHIT! an exclamation of irritation, fury, disappointment → 1962 sl.
► HELL’S BELLS! an exclamation of irritation or disappointment → 1832
► HELL’S BELLS AND BUCKETS OF GRAVY! an exclamation of irritation or disappointment → 2003 NZ
► HELL’S BELLS AND BUGGY WHEELS! an exclamation of irritation or disappointment → 1985 UK
► HELL’S BOOTS! an exclamation of irritation or disappointment → 1936 UK
► HELL’S BRITCHES! an exclamation of irritation or disappointment → 1928 UK
► HELL’S FIRE! an exclamation of irritation or disappointment → 1838
► HELL’S FIRE AND LITTLE FISHES! an exclamation of irritation or disappointment → 1903 US
► HELL’S FLAMES! an exclamation of irritation or disappointment → 1934 US
► HELL’S FURY! an exclamation of irritation or disappointment → 1851
► HELL’S HOLY BELLS! an exclamation of irritation or disappointment → 1953 Aust.
► HELL’S LITTLE JERRYBELLS! an exclamation of irritation or disappointment → 1947 US
► HELL’S SMOKE! an exclamation of irritation or disappointment → 1919 UK
► HELL’S TEETH! an exclamation of irritation or disappointment → 1961 NZ
► HOW THE BEJESUS! expresses irritation, impatience, or surprise → 2017
► HOW THE CHRIST! expresses irritation, impatience, or surprise → 1978
► I’LL BE DAMNED! an exclamation of annoyance, irritation, surprise, etc. → 1728 sl.
► I’LL BE DOUBLE DAMNED! an exclamation of annoyance, irritation, surprise, etc. → 1944 US sl.
► I’LL BE JIGGERED! an exclamation of irritation or surprise → 1835 sl.
► I’LL BE JIG-SWIGGERED! an exclamation of irritation or surprise → 1910 US sl.
► I’LL BE JIMJAMMED! an exclamation of irritation or surprise → 1912 US sl.
► I’LL BE SWITCHED! exclamation of irritation, surprise, denial → 1838
► I’M DAMNED! an exclamation of annoyance, irritation, surprise, etc. → 1837 sl.
► I’M JIGGERED! an exclamation of irritation or surprise → 1835 sl.
► I’M JAMMED! an exclamation of irritation or surprise → 1914 Aust. sl.
► IN A FUNK irritated, bad-tempered → 1808
► IN A LATHER irritated, agitated, anxious → 1839
► IN A PISSY irritated, angry → 1992 NZ sl.
► IN A SWEAT irritated, impatient, anxious → 1715
► IN SOMEONE’S MUTTON irritating, getting under someone’s skin → 1826 sl.
► IT’LL GIVE YOU THE SQUIRMS it will horribly embarrass or irritate you → c1930
► LIZARD SHIT! an exclamation of irritation, fury, disappointment → 1975 sl.
► MY WIG! an exclamation of irritation, surprise, etc. → 1820 UK sl.
► MY WIG AND FEATHERS! an exclamation of irritation, surprise, etc. → 1847 UK sl.
► MY WIG AND WHISKERS! an exclamation of irritation, surprise, etc. → 1877 UK sl.
► MY WIGS AND EYES! an exclamation of irritation, surprise, etc. → 1825 UK sl.
► OH DEAR! a mild register of anxiety, irritation, regret, etc. → 1694 UK
► OH THE DICKENS! expresses irritation, exasperation, etc. → 1947 arch.
► ON THE RAG irritated, testy, bad-tempered → 1967 US sl.
► O POX! an exclamation of irritation and impatience → 1695 obs.
► P.M.O. irritating, annoying (Pissing Me Off) → 2005 sl.
► RAT DAMN IT! an exclamation of irritation → 1981 Aust. sl.
► ROT IT! an exclamation of irritation, disbelief, or dismissal → 1592
► ROT YOU ALL! expresses irritation or impatience → 1594
► SHIT! an exclamation of irritation, fury, disappointment → 1895 sl.
► SHIT AND ONIONS! an exclamation of irritation, fury, disappointment → 1982 sl.
► SHIT AND PISS! an exclamation of irritation, fury, disappointment → 1930 sl.
► SHIT ON RYE! an exclamation of irritation, fury, disappointment → 1978 sl.
► SHIT ON TOAST! an exclamation of irritation, fury, disappointment → 1983 sl.
► SHITTY! an exclamation of irritation, fury, disappointment → 1922 sl.
► SHUCKS! an exclamation expressing irritation, regret, or surprise → 1847
► SHUCKINS! an expression of annoyance, irritation, contempt, or disbelief → 1893 Amer. dial.
► SNAKESHIT! an exclamation of irritation, fury, disappointment → 1961 sl.
► SOAP SUDS! an exclamation of irritation or frustration → 1842 US sl.
► STRIKE! an exclamation of irritation, amazement, etc. → 1915 Aust. sl.
► STRIKE ALMIGHTY! an exclamation of irritation, amazement, etc. → 1965 Aust. sl.
► STRIKE ME BALMY! an exclamation of irritation, surprise, etc. → 1894 sl.
► STRIKE ME BLIND! an exclamation of irritation, surprise, etc. → 1873 UK sl.
► STRIKE ME BLUE AND PINK! ► STRIKE ME PINK AND BLUE! an exclamation of irritation, surprise, etc. → 1894 sl.
► STRIKE ME COMICAL! an exclamation of irritation, surprise, etc. → 1781UK sl.
► STRIKE ME DILLY! an exclamation of irritation, surprise, etc. → 1911 Aust. sl.
► STRIKE ME HANDSOME! an exclamation of irritation, surprise, etc. → 1988 NZ sl.
► STRIKE ME PINK! an exclamation of irritation, surprise, etc. → 1890 sl.
► STRIKE ME PINK AND BRINDLE! an exclamation of irritation, surprise, etc. → 1901 Aust. sl.
► STRIKE ME RED! an exclamation of irritation, surprise, etc. → 1916 Aust. sl.
► STRIKE ME SENSIBLE! an exclamation of irritation, surprise, etc. → 1845 UK sl.
► STRIKE ME SILLY! an exclamation of irritation, surprise, etc. → 1892 UK sl.
► STRIKE ME STUPID! an exclamation of irritation, surprise, etc. → 1704 UK sl.
► STRIKE ME SUNBURNT! an exclamation of irritation, surprise, etc. → 1890 UK sl.
► STRIKE ME UP A GUMTREE! an exclamation of irritation → 1919 Aust. sl.
► STRIKE ME UP A GUTTER! an exclamation of irritation, surprise, etc. → 1885 Aust. sl.
► TAKE A HIKE! expresses irritation; get lost! → 1970 colloq.
► THAT ROTS that’s irritating or unsatisfactory → 1981 US students’ sl.
► THUMB IN ONE’S EYE an irritation, an annoyance → 2003 US sl.
► TO HELL WITH YOU! used as an expression of irritation or anger → 1846 Amer. sl.
► UPON THE TEASE uneasy from trifling irritation → 1706 obs.
► WHAT A FERRUP expresses irritation, impatience, astonishment, etc. → 1679 Eng. dial., obs.
► WHAT A POX! ► WHAT THE POX! ► WITH A POX! exclamation of annoyance, irritation → 1607 sl.
► WHAT IN SAM HILL! an expression of irritation or impatience → 1839
► WHAT THE BEJESUS! expresses irritation, impatience, or surprise → 1953
► WHAT THE CHRIST! expresses irritation, impatience, or surprise → 1967
► WHAT THE HANOVER expresses irritation or impatience → 1902 Eng. dial. (Bk.)
► WHAT THE JESUS! an exclamation of irritation → 1908
► WHAT THE PIPER? used to express irritation or surprise → 1900 US sl.
► WHO THE JESUS! an exclamation of irritation → 2019
► WITH A FACE LIKE A CLENCHED FIST having a sour, irritated expression → 2012 UK sl.
► YOU MAKE ME TIRED you irritate me → 1883 sl., orig. US

NOUNS
► AGGRAVATION an irritating or exasperation act or circumstance; annoyance → 1792
► ALL-OVERS feelings of irritation → 1893
► ANNOYMENT something which causes annoyance or irritation; an annoyance, a nuisance → 1659
► ASS, THE anger, annoyance, irritation → 1964 Amer. sl.
► BALLS-ACHE an irritating or tedious situation, experience, etc. → 1938 UK sl.
► BODERATION ► BOTHERATION irritation, annoyance, a fuss → 1766
► BONE an irritation; an annoyance; an aggravation → 1944 US sl.
► BONE IN THE THROAT a source of continual irritation or annoyance → 1855
► BRAVOORA a mad-like degree of irritation or fury in man or beast → 1911 Sc. (Bk.)
► BUDGIES, THE a nervous or irritated condition → 1990 Amer. dial. (Bk.)
► BUGBEAR a cause of irritation, annoyance, or anxiety → 1552
► BULLSHIT an object or task that is seen as annoying, irritating or ‘nonsense’ → 1922 UK sl.
► CANKER anything that corrupts, destroys, or irritates → 1981 Aust. colloq. (Bk.)
► COUROUCE ► COUROUX irritation, anger → a1450 obs.
► DICK irritation, annoyance → 2018 US sl.
► DICKERY an irritating or messing around → 2018 UK sl.
► DOUCHEBAGGERY obnoxious or irritating behaviour → 2000 sl., orig. US
► DRAG a state of irritation or frustration → 1834 US sl.
► EFFERATION irritating action → 1684 obs.
► EXACERBATION irritation, embitterment → 1582
► EXASPERATION a being intensely irritated or exasperated → 1549
► EYE ACHE an irritation, a bore, a nuisance → 1998 sl.
► FUCKER a difficult or irritating thing or task → 1975 sl.
► FUCK-OFF an irritating or frustrating situation → 2000 UK sl.
► FUNK a black mood; a state of depression; irritation, bad temper; a fit of gloom → 1808 orig. Sc.
► GADFLY an irritating or provoking thing → 1622
► GALL a state of irritation or mental soreness → 1591
► GOAT-GETTING a provoking irritation, anger, or annoyance, especially deliberately → 1910 colloq.
► GRATING irritation, fretting, harassing → 1716
► GROUCHIES a mood of depression, annoyance, or irritation; a sully or gloomy fit → 1965 Amer. dial.
► HAEMORRHOID an irritation; an annoying person → 1975 US sl.
► HEEBIE-JEEBIES, THE ► HEEBY-JEEBIES, THE a fit of irritation or depression → 1927 US sl.
► IRRITANCY an irritating quality or character; irritation, annoyance → 1834
► ISH something irritating → 2009 African-American sl.
► JEREMY BEADLE irritation, annoyance → 1992 UK rhyming sl. with ‘needle’
► JITTERS, THE a feeling or bout of irritation or nervousness; annoyance → 1933 sl.
► KIPPAGE a state of irritation or excitement → 1808 Sc.
► LATHER a state of irritation, anxiety, agitation, etc. → 1839
► MAD anger, irritation; a fit of anger → 1867 Amer. dial.
► MENACE something which is an irritation, annoyance, or inconvenience → 1851
► MONKEY TRICKS any action considered irritating or annoying → 1905 UK sl.
► NARK an annoying or unpleasant thing or situation; a source of irritation; also, a fit of anger or pique → 1918 sl.
► NEEDLE resentment, bitterness, irritation → 1899 sl.
► NEEDLE, THE a fit of irritation or nervousness → 1887
► NEEDLING an irritating, annoying, or goading a person → 1941 sl.
► NETTLING irritation, provocation → 1566
► NIGGLE irritation, annoyance → 1865
► NOYANCE irritation, vexation, distress → 1400
► NUISANCE a source of irritation or annoyance → 1814
► PAIN an annoying situation; an irritation; anything considered unpleasant, typically a task one does not wish to perform → 1910s sl.
► PAIN IN THE ARSE ► PAIN IN THE ASS a source of irritation → 1971 US sl.
► PAIN IN THE BUM a nuisance; a source of irritation → 1982 sl.
► PAIN IN THE BUSTLE a source of irritation → 1935 US sl.
► PAIN IN THE HOLE a source of irritation → 2021 sl.
► PAIN IN THE NECK a source of irritation → 1894 US sl.
► PAIN IN THE PLASTER a nuisance; an irritation → 1998 UK sl.
► PAIN IN THE REAR END a nuisance; a source of irritation → 1998 UK sl.
► PEEVE a source of irritation or annoyance → 1909
► PET PEEVE a source of irritation or annoyance → 1917
► PINPRICK a minor irritation; a petty annoyance → 1853
► PINPRICKING a minor irritation or misfortune → 1864
► PIQUE irritation, anger, or resentment, resulting from a slight or injury, especially to one’s pride → 1551
► PRICK a thing that causes annoyance, irritation, or torment → c1384 obs.
► PRICKLE a cause of discomfort, contention, or irritation; something that pricks the mind or feelings; chiefly used in plural → 1638
► PRORITATION irritation; provocation, incitement → 1615 obs.
► PROVOCATION a cause of irritation, anger, or resentment → 1638
► R. A. ► RED ARSE ► RED ASS irritation, bad temper → 1969 US sl.
► RALLYKABOO irrelevant, irritating, activity → 1904 Aust. sl.
► RANIKABOO ► RANNICABOO ► REINIKABOO ► RINKABOO irrelevant, irritating, activity → 1879 US sl.
► RANNYGAZOO irrelevant, irritating, activity → 1923 UK sl.
► RED PANTS irritation, bad temper → 1975 US sl.
► REEDANESS a state of irritation or ill temper → 1880 Eng. dial.
► REVERIE a state of irritation or anger → 1425 obs.
► RIDING irritating, annoying, teasing → 1927 sl., orig. US
► RUBBER an irritating remark, a rebuke; a source of irritation or annoyance → 1699
► RUFFLED FEATHERS a state of irritation or anger → 1888
► RUFFLING an irritating or annoying → 1647
► RUNNING SORE a persistent problem; a constant nuisance or irritation → 1590
► SADDAM HUSSEIN a pain; an irritation → 1998 UK rhyming sl.
► SCOT a fit of irritation; a bad temper → 1859 sl.
► SCREAMING HEEBIE-JEEBIES, THE intense irritation → 1999 Aust. sl. (Bk.)
► SHEGARRY annoyance, irritation → 2001 Black British sl.
► SHIRTINESS irritation, ill temper → 1936
► SHITS, THE a being very irritated or annoyed → 1928 sl.
► SHIZNIT something irritating → 2005 African-American sl.
► SHIZZLE something irritating → 2000 African-American sl.
► SNARK irritation, tetchiness, anger → 2002 US sl.
► SNOTTINESS irritation, ill temper → 1955 sl.
► SORENESS distress or irritation; irritability, touchiness → c1000
► SORE PLACE a point or matter in respect of which one is easily vexed ore irritated → 1690
► SORE POINT a point or matter in respect of which one is easily vexed ore irritated → 1863
► SORE SPOT a point or matter in respect of which one is easily vexed ore irritated → 1690
► SPITE a feeling of annoyance or irritation → 1586 obs.
► STERKS, THE ► STURKS, THE a fit of irritation or annoyance → 1941 Aust. sl.
► STOMACH anger, irritation, malice, ill-will → 1540 obs.
► SWEAT a state of irritation, impatience, anxiety, etc. → 1715
► TEASING petty irritation → 1678
► TEEN irritation, vexation, annoyance → 1175 obs. exc. Sc.
► THUMB IN ONE’S EYE, A an annoyance; a constant irritant → 1970s US sl.
► TORMENT an instrument of irritation or annoyance → 1882
► VEXATION irritation, annoyance, dissatisfaction → 1782
► WASP something that irritates or offends one → 1588

NOUNS – PERSON
► A-HOLE an irritating, obnoxious, or stupid person → 1942 sl.
► ANKLE-BITER a person regarded as relatively unimportant but nevertheless irritating or annoying → 1872 colloq., chiefly US
► ARSEHOLE a stupid, irritating, or despicable person; a person who behaves contemptibly → 1928
► ASSHOLE a stupid, irritating, or contemptible person; a person who behaves despicably → 1962 US sl.
► BALL-BREAKER a tedious, irritating person → 1971 African-American sl.
► BALL SACK an irritating, obnoxious, or objectionable person → 1991 sl.
► BIDDY an old woman, generally irritating or interfering; a fussy, mean, or quarrelsome old woman; usually as ‘old biddy’ → 1833 sl.
► BIG DRINK OF WATER an irritating person, a bore → 1960 US sl.
► BOD a tedious, intrusive, pretentious, or otherwise irritating person → 1980s UK sl.
► BUG an irritating person → 1866 US sl.
► BUMHOLE an irritating, contemptible, or stupid person → 1967 sl.
► BUTTHOLE a stupid, irritating, or contemptible person; a person who behaves badly → 1962 US sl.
► CLEVER BOOTS an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1846 colloq., disparaging usage
► CLEVER CLOGS an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1866 colloq., disparaging usage
► CLEVER DICK an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1892 colloq., disparaging usage
► CLEVER JACK an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1864 colloq., disparaging usage
► CLEVERKINS an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1916 colloq., disparaging usage
► CLEVERSIDES an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1876 colloq., disparaging usage
► CLEVERSTICKS an irritating or smug person who would like to be thought of as intelligent or knowledgeable → 1930 colloq., disparaging usage
► CLOWN an irritating, incompetent, or ignorant person → 1566
► CRACK BABY an irritating person; a term of abuse → 1993 US sl.
► CULO an irritating, objectionable, or stupid person → 1972 sl., often derogatory
► D-BAG an irritating or obnoxious person (Douche Bag) → 1984 sl., orig. US
► DRINK OF WATER an irritating person, a bore → 1933 sl.
► FACE-ACHE an ugly, irritating, or miserable-looking person → 1988 Aust. & Brit. sl. (Bk.)
► FASSY an irritating, contemptible, or stupid person → 2002 sl.
► FASSYHOLE an irritating, contemptible, or stupid person → 1997 Jamaican sl.
► FRETTER a person who irritates → 1504
► FUCK BOI ► FUCKBOY an irritating male → 2016 African-American sl.
► FUME a person who is likely to become angry or irritated → 1768
► GADFLY an irritating or provoking person; a person who persistently criticizes or challenges the status quo or those in authority, in an attempt to stimulate change → 1622
► GALLER one who galls or irritates → 1674
► GALLSTONE an irritating person → 1961 US sl.
► GAWDELPUS ► GAWD-HELP-US a helpless, irritating, or exasperating person → 1912 jocular usage
► GOAT-GETTER a person who deliberately makes another person irritated, annoyed, or angry → 1908 colloq.
► GRANNY GRUNT a fussy, irritating person, not necessarily female or old → 1997 rhyming sl. for ‘cunt’
► GREASER an irritating, contemptible, or objectionable person → 1900 UK sl.
► GUT-ACHE ► GUTS-ACHE an irritating person → 1954 NZ sl.
► HADDIE ► HADDOCK (AND COD) a term of abuse; a sod, an annoying, irritating, or unpleasant person → 1831 UK rhyming sl. for ‘sod’
► HAEMORRHOID an annoying or irritating person → 1975 US sl.
► HANG-UP a boring, irritating person → 1968 US sl.
► HO-BAG an irritating or objectionable person, especially a woman → 1989 US sl., derogatory
► HOSEBAG an irritating or obnoxious person of either gender → 1974 US sl., derogatory
► JACKHOLE an irritating, contemptible, or stupid person → 1996 sl., chiefly US
► JACK SPRAT a brat, an irritating small child → 1935 rhyming sl.
► JERKFACE an irritating, or contemptible person → 1942 US sl., derogatory
► JERKO an irritating, or contemptible person → 1949 colloq.
► KNOB-HEAD a stupid, irritating person → 2012 Brit. sl. (Bk.)
► LITTLE PERISHER an irritating or mischievous child → 1935 colloq.
► LONG DRINK OF WATER an irritating person, a bore → 1975 US sl.
► MENACE a person that is a bore or a general nuisance; someone or something very troublesome or annoying; an unpleasant, irritating person → 1936 colloq.
► MOTHBALL an insignificant or foolish person; an obnoxious or aggravating person; a teenage jerk; an irritating person; an over-diligent student → 1944 US sl.
► MOTO a tedious, irritating, boring person → 1990 US students’ sl.
► NARK an irritating person, a spoilsport, a badly behaved person → 1838 sl., chiefly Aust. & NZ sl.
► NARKER an irritating person, a spoilsport, a badly behaved person → 1911 sl., chiefly Aust. sl.
► NEEDLER a person who irritates, goads, or torments others → 1874
► NETTLER one who irritates → 1611
► NUDNIK an irritating, pestering, or nagging person → 1916 US colloq, chiefly Jewish usage
► NUTSACK an irritating, obnoxious, or objectionable person → 1984 sl.
► PAIN an annoying person or irritating person  → 1926
► PAIN IN THE NECK an irritating nuisance → 1941 UK sl.
► PAIN IN THE PUKU an irritating person (puku – Maori for stomach) → 1998 NZ sl. (Bk.)
► PERISHER an irritating or mischievous child → 1896 colloq., chiefly UK
► PINTLE a small, irritating person → 1969 Ireland sl.
► PISS-ANT an insignificant, contemptible, or irritating person → 1918 disparaging usage
► PLAGUE an irritating person → 1450
► POOH-BRAIN an irritating person → 1958 US students’ sl., euphemism for shithead
► POO-HEAD an irritating person → 1989 US sl., euphemism for shithead
► R. A. ► RED ARSE a person who is chronically irritated; a grouch → 1961 US sl.
► SCONE-DOER a person subject to sudden fits of excitement and irritation → 1942 NZ sl.
► SINEX an annoying or irritating person → Brit. sl.
► SLAGBAG an irritating or objectionable person → 1966 sl., derogatory
► SLUTBAG an irritating or objectionable person → 1987 sl., derogatory
► SOD an irritating or troublesome person → 1835
► STIFFY an irritating person → 1960 US sl.
► TARYER a provoker, a vexer; one who irritates → c1440 obs.
► TEASE a person who enjoys playfully irritating, provoking, or annoying others → 1852 colloq.
► TIGHTARSE ► TIGHTASS an irritating parent → 2001 Aust. sl.
► WICK an irritating or bad-tempered person → 1988 Sc. sl.
► WOOLLY VEST an annoying person; a pest → 1998 UK rhyming sl.

VERBS
► AG ► AGG to irritate, as by teasing → 1908 Sc.
► AGGERPERVOKE to aggravate, to irritate, to provoke, to annoy → 1923 Amer. dial.
► AGGRANOY ► AGRANOY to irritate, to annoy → 1895 sl.
► AGGRATE to irritate → 19C Eng. dial.
► AGGRAVATE to irritate, to annoy → 1598 colloq.
► AGGRAWOKE to irritate, to annoy → 1848 Aust. sl.
► AGGROVOKE ► AGROVOKE to annoy, to irritate → 1900 Aust. sl.
► AMARICATE to irritate, embitter, to be a source of irritation → 1651 obs.
► ATENE to irritate, to vex, to annoy → 1320 obs.
► BITCH OFF to irritate, to annoy → 1975 US students’ sl.
► BITCH SOMEONE UP of a woman: to irritate or cause trouble for a man, as a boyfriend, by flirting or playing ‘feminine’ games → 1959 US sl.
► BITE to irritate, to annoy, to worry → 1614 sl.
► BITE ONE’ S ASS to irritate, to annoy, to worry → 1952 US sl.
► BOOG to irritate, to annoy → 1934 African-American sl.
► BOSH to cause trouble for; to irritate → 1870 sl.
► BRASS OFF to irritate or annoy a person → 1925 sl., orig. Services’ usage
► BRINDLE to be irritated, to show resentment, to bridle up → 1875 Eng. dial.
► BRINGLE to irritate, to anger → 1983 UK sl.
► BROWN OFF to irritate, to annoy → 1916 sl., orig. military usage
► BUCK to show irritation; to object to protest → 1851 sl.
► BUG to bother, to annoy, to irritate, to vex, to infuriate → 1947 Amer. dial.
► BUM KICK to annoy, to irritate → 1967 US sl.
► BUM OUT to irritate → 1970 colloq.
► BURN SOMEONE’S BUTT to annoy, to irritate someone → 2001 US sl.
► BURN UP to irritate, to annoy, to aggravate → 1926 Amer. dial. 
► BUZZ to annoy, to irritate → 1915 Amer. sl.
► CAG ► KEG to irritate; to annoy; to affront; to anger → 1801 Eng. dial.
► CARRY THE CAG to be vexed, sullen; to be easily irritated; to lack a sense of humour, esp. as regards jokes against oneself → 1811 sl.
► CHAFE to vex, to irritate → 1400
► CHAP SOMEONE’S ASS to irritate or annoy someone → 1968 US sl.
► CHAP SOMEONE’S REAR to irritate or annoy someone → 1961 US sl.
► CHEESE OFF to irritate, to annoy, to frustrate → 1946 colloq., chiefly UK
► CHEW ON to irritate, to pester, to nag → 1933 US sl.
► COP THE NEEDLE to be irritated or annoyed → 1873 UK sl.
► CRAB to cross; to put out of humour or temper; to irritate, to anger, to enrage, to provoke → a1400 obs.
► CRAP ► CROP to irritate, to annoy → 1865 sl.
► CRAP SOMEONE AROUND to irritate, to annoy → 1975 US sl.
► CROP to irritate, to annoy → 1865 sl.
► CURDLE to irritate, to cause annoyance → 1941 US sl.
► CUT THE COMEDY to stop doing something considered irritating or foolish → 1915 sl.
► DICK SOMEONE AROUND to  irritate, to impose on, to harass → 1982 US sl.
► DIG to bother, to irritate one → 1967 Amer. dial.
► DOG to irritate, to pester → 1902 sl.
► DO ONE’S NUT ► DO THE NUT to have a tantrum; to become extremely angry, irritated or agitated → 1919 colloq.
► DRAG to irritate, to bore, to ‘bring down’ → 1915 US sl.
► DRAW to irritate, to exasperate → 1876 colloq. obs.
► DRAW WOOL to irritate; to foment a quarrel → 19C tailors’ sl., obs.
► DRAW WORSTED to irritate; to foment a quarrel → 19C tailors’ sl., obs.
► DRIVE to irritate someone intensely → c1950 Aust. teen sl.
► EAGER to excite, to irritate, to provoke; to become exasperated → c1374 obs.
► EAT ONE UP to irritate one greatly → 1995 US sl. (Bk.)
► EDGE to irritate or annoy a person → 1886
► EGG to tease, to annoy, to pester, to irritate; to importune, to find fault continually, to nag → 1500 obs. exc. Eng. & Amer. dial.
► ENCHAFE to irritate, to excite → 1374 obs.
► ENEAGER to irritate; to make eager or fierce → 1594 obs.
► ENGRAGE to irritate, esp. by satire → 1900 Sc. (Bk.)
► ERK to annoy, to irritate → 2000 African-American sl.
► ERT to urge onward, to incite; to irritate, to provoke → 1440 obs.
► EXACERBATE to irritate, to provoke → 1660
► EXASPERATE to  irritate a person; to provoke to anger → 1534
► EXULCERATE to exasperate, to irritate; to aggravate a disease or sorrow → 1593
► FART ABOUT to irritate → 1986 UK sl.
► FAUNCH to fret, to worry; to show irritation or impatience; to complain, to sulk → 1970 Amer. dial.
► FLAKE OFF to irritate; to act in an irritating manner → 1969 US students’ sl.
► FLY SALTY to be annoyed or irritated; to take offense → 1969 sl., orig. African-American
► FRAB to harass, worry, fret, fidget; to irritate, excite → 1848 Eng. dial.
► FRET to irritate, to annoy, to distress → 1535
► FRET AND FUME to exhibit anger or irritation → c1522
► FROST to irritate, to annoy, to anger → 1910 sl., chiefly US
► FUCK OFF to irritate or annoy a person → 1973 sl.
► FUCK OUT to irritate, to annoy → 2012 sl.
► FUME to be angry or irritated → c1522
► FUME AND CHAFE to exhibit anger or irritation → 1535
► FUSSOCK with about: to make a fuss, to bustle about quickly; to fidget, to irritate → 1892 Eng. dial.
► GALL to annoy, to vex, to irritate, to hurt in feeling; to chafe, to fret, to become pettish → 1573
► GET ACROSS to irritate, to annoy → 1911 sl.
► GET IN SOMEONE’S ASS to irritate, to annoy → 1959 US sl.
► GET IN SOMEONE’S HAIR to annoy or irritate someone → 1935 US sl.
► GET IN WRONG to irritate, to annoy → 1910 sl.
► GET OFF SOMEONE’S TIP to stop being irritating → 1986 US sl.
► GET ON SOMEONE’S GINGER to irritate → 1993 Aust. sl.
► GET ON SOMEONE’S GOAT to irritate, to annoy → 1905
► GET ON SOMEONE’S NERVES to be a source of irritation or anxiety to a person → 1891
► GET ON SOMEONE’S QUINCE to irritate, to exasperate a person → 1941 Aust. sl.
► GET ON SOMEONE’S QUOIT to irritate, to annoy → 1943 Aust. sl.
► GET ON SOMEONE’S RASPBERRY to irritate → 1960 UK sl.
► GET ON SOMEONE’S TITS to irritate intensely; to get on the nerves of → 1945 sl.
► GET ON SOMEONE’S WHEEL to irritate, to pester someone → 1968 Aust. sl.
► GET ON SOMEONE’S WICK to irritate, to annoy → 1937
► GET SOMEONE’S ANGORA to annoy, to irritate → 1912 US sl.
► GET SOMEONE’S ASS UP to irritate, to annoy, to infuriate → 1884 US sl.
► GET SOMEONE’S BACK UP to irritate, to annoy, to infuriate → 1774 sl.
► GET SOMEONE’S FUR UP to annoy, to irritate → 1919 US sl.
► GET SOMEONE’S GOAT ► GET SOMEONE’S GOAT UP to irritate, to annoy; to get the best of one → 1906
► GET SOMEONE’S HUMP UP to become irritated → 1860 UK sl. (Bk.)
► GET SOMEONE’S INDIAN UP to irritate, to anger → 1871 US sl.
► GET SOMEONE’S NANNY to irritate, to annoy one → 1908 Amer. dial.
► GET SOMEONE’S NANNY-GOAT to irritate, to annoy or infuriate one → 1914 sl.
► GET THE DEAD NEEDLE to become irritated or annoyed → 1958 UK sl.
► GET THE HARDNOSE to become angry or irritated → 1928 Amer. dial.
► GET THE MISERIES to be irritated → 1997 US
► GET THE MONKEYS to have feelings of irritation → 1916 UK sl.
► GET THE NEEDLE to become irritated or annoyed → 1884 UK sl.
► GET THE PRICKER to become angry, irritated or sulky → 1945 Aust. & NZ sl.
► GET THE SPIKE to be extremely irritated or annoyed → 1895 UK sl.
► GET UNDER ONE’S HIDE to irritate, to annoy, to frighten someone → 1966 Amer. dial.
► GET UNDER ONE’S SKIN to irritate; to become constantly irritating → 1896 UK
► GET UP SOMEONE’S BUTT to irritate, to annoy → 2021 US sl.
► GET UP SOMEONE’S NOSE to annoy, to irritate → 1917 sl., orig. US
► GIG to irritate, to annoy → 1919 Aust. & US sl.
► GIVE SOMEONE AN ACHE to irritate someone → 1906 US sl.
► GIVE SOMEONE AN ACHE IN THE BACK OF THE LAP to irritate someone → 1939 US sl.
► GIVE SOMEONE A PAIN IN THE ASS to irritate someone → 1934 US sl.
► GIVE SOMEONE A PAIN IN THE BEHIND to irritate someone → 1934 US sl.
► GIVE SOMEONE A PAIN IN THE BUM to irritate someone → 1959 UK sl.
► GIVE SOMEONE A PAIN IN THE CAN to irritate someone → 1956 US sl.
► GIVE SOMEONE A PAIN IN THE EAR to irritate someone → 1925 US sl.
► GIVE SOMEONE A PAIN IN THE FACE to irritate someone → 1925 sl.
► GIVE SOMEONE A PAIN IN THE FOOT to irritate someone → 1905 US sl.
► GIVE SOMEONE A PAIN IN THE GUTS to irritate someone → 1953 sl.
► GIVE SOMEONE A PAIN IN THE NECK to irritate someone → 1894 US sl.
► GIVE SOMEONE A PAIN IN THE PANTS to irritate someone → 1933 UK sl.
► GIVE SOMEONE A PAIN IN THE TAIL to irritate someone → 1944 UK sl.
► GIVE SOMEONE A PAIN IN THE TEAT to irritate someone → 1959 Aust. sl.
► GIVE SOMEONE A SNAKE to irritate, to annoy → 1902 UK sl.
► GIVE SOMEONE GYP to hurt a person, to cause pain for; hence, to cause trouble for, to irritate or distress → 1894
► GIVE SOMEONE THE HUMP to irritate, to annoy → 1884 sl.
► GIVE SOMEONE THE IRRITS to annoy or irritate → 1984 Aust. sl.
► GIVE SOMEONE THE JIMMY BRITTS to irritate, to unnerve → 1957 Aust. sl.
► GIVE SOMEONE THE NEEDLE to irritate → 1879 sl.
► GIVE SOMEONE THE PIP to annoy or irritate; to make angry, bad-tempered, or dispirited → 1881
► GIVE SOMEONE THE SHITS to annoy or irritate → 1928 Aust. & NZ sl.
► GIVE SOMEONE THE SPIKE to irritate → 1889 Aust. sl.
► GIVE SOMEONE THE SPUR to irritate, to annoy → 1905 UK sl.
► GIVE SOMEONE THE STERKS  to irritate, to annoy → 1941 Aust. sl.
► GIVE SOMEONE THE THREEPENNIES to irritate someone, to annoy → 1963 Aust. sl.
► GIVE SOMEONE THE TOMTITS to irritate or annoy a person greatly → 1944 chiefly Aust. & NZ
► GIVE SOMEONE THE WORMS to exasperate, to irritate, to annoy → 20C Aust. sl.
► GIVE THE KNOCK TO to irritate, to disconcert → 1899 UK sl.
► GOOB to act irritatingly → M19 sl.
► GRAB to irritate → 1961 US sl.
► GRATE to irritate, to fret, to harass → 1555
► GRATE UPON to have an irritating effect upon → 1631
► GRAVEL to irritate; to annoy → 1794
► GREISSEL to disgust, to sicken, to nauseate, to irritate → 1939 Amer. dial.
► GRIG to irritate, to annoy → 1553
► GRILL to provoke, to annoy, to irritate, to offend → 897 obs.
► GRIP ONE’S ASS ► GRIPE ONE’S BUTT to annoy someone; to bother or irritate someone → 2006 US sl. (Bk.)
► GRIPE ONE’S ASS to annoy someone; to bother or irritate someone → 1993
► GRIPE ONE’S BUTT to annoy someone; to bother or irritate someone → 2006 US sl. (Bk.)
► HACK ► HACK OFF  to annoy, to irritate, to anger; to provoke; to goad → 1881 Amer. sl.
► HACKLE UP to become irritated or angry → 1935
► HAG ► HAGG excite to quarrel; to provoke, to irritate; to annoy, to incite; to complain, to find fault  → 1806 Eng. & Amer. dial.
► HARD-TIME to irritate someone or scold them → 1964 US sl.
► HAUL to irritate, to pester → 1750 sl.
► HAVE A HARDNOSE to become angry or irritated → 1939 Amer. dial.
► HAVE A PICK AT to irritate, to annoy, to nag at → 1895 Aust. sl.
► HAVE NO PATIENCE WITH to be irritated by; to be unable to tolerate → 1682
► HAVE THE DEAD NEEDLE to be irritated with someone → 1959 sl.
► HAVE THE NEEDLE to be irritated with someone → 1939 sl.
► HAVE THE PRICKER to be angry, irritated or sulky → 1945 Aust. & NZ sl.
► HAVE THE SHITS to be irritated or annoyed → 1985 Aust. sl.
► HAVE THE SPIKE to be irritated or angry → 1897 sl.
► HEAD IN WRONG to irritate, to annoy → 1914 sl.
► HELL-HACK to irritate, to annoy; to embarrass → 1934 US sl.
► HONK OFF to irritate, to annoy → 1970 colloq.
► HUFF ► HUFF IT to swell with irritation or anger; to get out of temper → 1598 obs.
► HYPE to irritate deliberately; to annoy → 1970 US students’ sl. (Bk.)
► IRE to irritate, to anger → 1420 obs.
► IRRITE to irritate → 1450 obs.
► JACK UP to reprove severely, to reprimand; to scold; to irritate → 1896 Amer. dial.
► JACK WITH to irritate, to annoy → 1987 US sl.
► JAG to vex, to irritate, to annoy, to trouble; to pain, to rankle → 1888 Eng. dial.
► JAG OFF to annoy, to irritate, to play tricks on; to disparage; to reject → 1968 Amer. dial.
► JIG to irritate, to bother → 1999 US sl.
► JUMP SALTY to be annoyed or irritated; to take offense → 1938 sl., orig. African-American
► KAIM AGAINST THE HAIR to oppose, to ruffle, to irritate (kaim = comb) → 1768 Sc.
► KECKLE to get irritated or angry → 1866 Sc.
► KEG to irritate; to annoy → E19 Eng. dial.
► MADDEN to irritate, to annoy, to vex → 1720
► MAKE IGNORANT to irritate, to annoy → 1977 UK criminals’ sl.
► MAKE SOMEONE’S BRISTLES RISE to irritate, to infuriate → M19 sl.
► MAKE SOMEONE’S NIPPLES ACHE to irritate, to annoy → 1950s sl.
► MAKE TIRED to get on the nerves of, to irritate → 1883
► MAR to annoy, to irritate → 1905 Eng. dial. (Bk.)
► MIFF to put a person out of humour; to offend, to irritate somebody → 1811
► MISPAY to irritate, to anger → 1225 obs.
► MITHER to irritate, to pester, to bother → 1848 orig. Eng. dial.
► MUCK ► MUCK ABOUT to irritate, to tease → 1888 UK sl.
► NAG to irritate → 1801
► NARK to annoy, to vex, to irritate, to exasperate; to infuriate; to become annoyed → 1860 Eng. dial. & sl.
► NEEDLE to annoy, to irritate → 1812 sl.
► NETTLE 1. to irritate, to vex, to anger, to provoke → 1450
2. to become irritated or annoyed → 1810 obs.
► NIGGLE to irritate, to cause a slight but persistent annoyance → 1796 UK colloq.
► NIT-SHIT to talk in an irritating manner → 1967 US sl.
► NUDGE ► NUDGY to bother, to irritate → 1971 sl.
► NUDZH to bother, to irritate → 1980 sl.
► OFGRAME to vex, to irritate → c1200 obs.
► OFTENE to irritate → a1250 obs.
► PEE OFF to irritate, to annoy → 1946  sl.
► PEEVE to irritate, to annoy → 1901 orig. US
► PESTER to act in a persistently irritating, vexing, or demanding manner → 1585
► PICK AT to irritate, to annoy, to nag at → 1895 Aust. sl.
► PIQUE to irritate, to wound the pride of, to offend → 1671
► PISS ABOUT ► PISS AROUND to irritate or tease someone → 1978 sl.
► PISS-BALL ABOUT to act in a futile or an irritating manner → c1920 sl.
► PISS OFF to annoy, to irritate, to depress a person → 1946 sl.
► PISS ON ONE’S CHIPS to irritate, to annoy → 1976 UK sl.
► PISS ON ONE’S CHIPS AND TELL THEM IT’S VINEGAR to irritate, to annoy → 2013 UK sl.
► PLAY JIP to irritate → 1949 Aust. sl.
► PLAY UP to irritate, to ‘mess around’ → 1803 chiefly UK
► POKE to stir up; to incite, to goad, to irritate → c1400
► POKE UP to irritate, to provoke → 1894 Anglo-Indian
► PRAT ABOUT ► PRAT AROUND to act in an irritating manner → 1983 UK sl.
► PRESS SOMEONE’S BUTTONS to make another angry or disturbed, to annoy, to irritate → 1936 Amer. sl.
► PRORITATE to stir up, to provoke, to irritate, to incite → 1620 obs.
► PROVOKE to irritate, to annoy, to vex, especially deliberately → 1425
► PULL SOMEONE’S CHAIN to irritate, to tease, to ‘wind up’ → 2025 US sl.
► PULL SOMEONE’S STRING to irritate, to tease, to ‘wind up’ → 2017 sl.
► PUNGE to cause a part of the body to smart; to irritate, to sting → 1657 obs.
► PUSH SOMEONE’S KEY to irritate one, to tease one → 1992 US prison sl.
► PUT ON to annoy; to irritate → 1963 US sl.
► PUT ONESELF IN SOMEONE’S FACE to irritate, to annoy → 1959 US sl.
► PUT OUT to irritate, to annoy → 1796
► PUT SOMEONE’S BACK UP to irritate, to annoy, to infuriate → 1864 sl.
► PUT SOMEONE’S BALLS IN A KNOT to discomfit, to embarrass, to irritate → 1930 Aust. sl.
► PUT SOMEONE’S TITS IN A TANGLE to irritate someone → 2003 Aust. sl.
► RAFT to irritate; to disturb, to unsettle → 1851 Eng. dial.
► RANKLE to fret or chafe angrily, to be or become irritated → 1487
► RASP to grate upon, to irritate → 1810
► RASP ON to grate upon or irritate → 1898
► RATTLE to irritate, to nettle → 1865
► RATTLE ONE’S CAGE to irritate, to annoy, to nag → 1976 US sl.
► REAR UP to become irritated, mad, or angry → 1842 Amer. dial.
► REAR UP ON ONE’S HIND LEGS to become irritated, mad, or angry → 1842 Amer. dial.
► REGRATE to have an irritating effect on → 1661 obs.
► REHETE to annoy, to provoke, to irritate → 1447
► RIDE to irritate, to annoy → 1891 colloq., orig. US
► ROIL ► ROYLE to disturb in temper; to irritate, to make angry → 1734
► ROUGHEN to irritate, to ruffle → 1859
► ROUGHEN UP to irritate, to ruffle → 1837
► ROUGH UP to upset, to irritate, to ruffle → 1877
► RUB to irritate; to annoy → 1450
► RUB THE WRONG WAY to annoy, to irritate → 1834
► RUCK to grow irritated or angry → 1890 sl., obs.
► RUFFLE to annoy, to irritate, to vex → 1658
► SET SOMEONE’S BACK UP to irritate, to annoy, to infuriate → 1883 sl.
► SET SOMEONE’S TEETH ON EDGE to irritate or annoy a person → 1565
► SET UP ONE’S HECKLE to become irritated or angry → 1601 obs.
► SHIT ► SHIT OFF to irritate, to annoy → 1974 Aust. sl.
► SHOG to irritate, to annoy → 1639 obs.
► SNAG to irritate or scold in an aggravating manner → 1866 Eng. dial.
► SNARK ► SNARK OFF to make irritated → 1999 US sl.
► SNOOTY easily irritated, short-tempered → 1959
► SORE UP to irritate, to annoy → 1929 sl.
► SPITE to irritate, to annoy, to offend → 1563
► SPUR to irritate, to annoy → 1879 UK sl.
► STEW ► STEW OVER to be irritated, concerned, or worried; to irritate → 1917 US sl.
► STICK PINS INTO to irritate or annoy → 1879
► STRESS to cause irritation for someone → 1994 US sl.
► STROKE AGAINST THE HAIR to irritate, ruffle, or cross a person → 1846 Sc.
► STROKE THE FUR THE WRONG WAY to cause irritation → 1870
► STROKE THE WRONG WAY OF THE HAIR to irritate, to ruffle, to cross a person → 1860
► STUNT to irritate, to provoke to anger → 1583 obs.
► TAISLE to tease, to irritate, to vex → 1825 Sc.
► TAIVER ► TAVER  to annoy, to vex, to irritate; to bewilder or confuse with much talking or questioning; to lead astray → 1861 Sc.
► TAKE PEPPER IN THE NOSE to take offense; to become angry or irritated; to be vexed; to mistrust → 1787
► TAR ► TARRE to irritate, to vex, to provoke → a1000 obs.
► TEEN to irritate, to vex, to annoy, to anger →  c1000 obs.
► TEE OFF to anger, to annoy → 1955
► TERRIFY to annoy, to irritate; to tease, to worry → 1641 obs. exc. Eng. dial.
► TICKLE to vex, to irritate, to provoke → 1547 obs.
► TICK OFF to irritate, to annoy → 1960 US sl.
► TIFF to excite; to irritate → 1905 Eng. dial. (Bk.)
► TITILLATE to irritate slightly → 1837
► TOUT to irritate, to vex, to tease → 1725
► TREAD ON SOMEONE’S COAT-TAILS to irritate or annoy someone → 1859
► TWINGE to irritate → 1647 obs.
► TWIST SOMEONE’S BALLS to irritate, to anger → 2005 US sl.
► ULCERATE to irritate → 1647
► URGE to irritate or annoy; to provoke to anger → 1593
► URN to pain, to irritate → 1470 obs.
► URP to annoy, to bother, to irritate → 1967 Amer. dial.
► URTICATE to irritate to indignation, etc.; to goad, to nettle → 1873
► VELLICATE of things: to act upon or affect so as to irritate; to nip, to pinch, to tear a part of the body by means of small or sharp points → 1604
► WIG to irritate, to annoy → 1861 sl.
► WIND UP to irritate, annoy, or provoke someone deliberately or intentionally → 1961 colloq.
► WORK ONE’S LAST NERVE ► WORK ONE’S NERVES  to annoy, to irritate → 1990 African-American & students’ sl.
► WRETHE to vex, to anger, to irritate → c900 obs.
► YAG to make a noise; to talk angrily; to importune incessantly; to irritate, to nag; to quarrel → 1892 Sc. & Eng. dial.
► YANK SOMEONE’S CHAIN to irritate someone; to annoy someone; to remind or distract someone forcibly → 1991 sl.
► YANK SOMEONE’S CRANK to irritate someone; to annoy someone; to remind or distract someone forcibly → 2001 sl.
► YARK to be an irritation to → 1583 Sc.
► YIP to talk in a petulant or irritating manner → 1918 US sl.