ETYMOLOGY
from Anglo-Norman meseisé, miseisé, mysesé (sick, unhappy, suffering, painful),
from mesaiser (misease, to trouble, to distress)
EXAMPLE 1
“…A lodlich musel he þouȝte al-so : and þe fouleste þat miȝte beo—
A Miseisiore man þane he þouȝte : no man ne miȝte iseo …”
From:
The early South-English legendary ; or, Lives of Saints
Edited by Carl Horstmann, 1887
Vita sancti Iuliani boni hospitis (The life of St. Julian the Hospitable). c1300
EXAMPLE 2
It had been a long, hard day, and I went to bed that night feeling miseasy and heart-sick.
Lexicophilia 